Scoliosis Follow-Up Using Noninvasive Trunk Surface Acquisition

Adolescent idiopathic scoliosis (AIS) is a musculoskeletal pathology. It is a complex spinal curvature in a 3-D space that also affects the appearance of the trunk. The clinical follow-up of AIS is decisive for its management. Currently, the Cobb angle, which is measured from full spine radiography, is the most common indicator of the scoliosis progression. However, cumulative exposure to X-rays radiation increases the risk for certain cancers. Thus, a noninvasive method for the identification of the scoliosis progression from trunk shape analysis would be helpful. In this study, a statistical model is built from a set of healthy subjects using independent component analysis and genetic algorithm. Based on this model, a representation of each scoliotic trunk from a set of AIS patients is computed and the difference between two successive acquisitions is used to determine if the scoliosis has progressed or not. This study was conducted on 58 subjects comprising 28 healthy subjects and 30 AIS patients who had trunk surface acquisitions in upright standing posture. The model detects 93% of the progressive cases and 80% of the nonprogressive cases. Thus, the rate of false negatives, representing the proportion of undetected progressions, is very low, only 7%. This study shows that it is possible to perform a scoliotic patient's follow-up using 3-D trunk image analysis, which is based on a noninvasive acquisition technique.IRSC / CIH

The flavor symmetry in the standard model and the triality symmetry

A Dirac fermion is expressed by a 4 component spinor which is a combination of two quaternions and which can be treated as an octonion. The octonion possesses the triality symmetry, which defines symmetry of fermion spinors and bosonic vector fields. The triality symmetry relates three sets of spinors and two sets of vectors, which are transformed among themselves via transformations $G_{23}, G_{12}, G_{13}$, $G_{123}$ and $G_{132}$. If the electromagnetic (EM) interaction is sensitive to the triality symmetry, i.e. EM probe selects one triality sector, EM signals from the 5 transformed world would not be detected, and be treated as the dark matter. According to an astrophysical measurement, the ratio of the dark to ordinary matter in the universe as a whole is almost exactly 5. We expect quarks are insensitive to the triality, and triality will appear as three times larger flavor degrees of freedom in the lattice simulation.Comment: 16 pages 8 figures, To be published in International Journal of Modern Physics

Multivariate Lagrange inversion formula and the cycle lemma

International audienceWe give a multitype extension of the cycle lemma of (Dvoretzky and Motzkin 1947). This allows us to obtain a combinatorial proof of the multivariate Lagrange inversion formula that generalizes the celebrated proof of (Raney 1963) in the univariate case, and its extension in (Chottin 1981) to the two variable case. Until now, only the alternative approach of (Joyal 1981) and (Labelle 1981) via labelled arborescences and endofunctions had been successfully extended to the multivariate case in (Gessel 1983), (Goulden and Kulkarni 1996), (Bousquet et al. 2003), and the extension of the cycle lemma to more than 2 variables was elusive. The cycle lemma has found a lot of applications in combinatorics, so we expect our multivariate extension to be quite fruitful: as a first application we mention economical linear time exact random sampling for multispecies trees

The QCD Potential at O(1/m)O(1/m)

Within an effective field theory framework, we obtain an expression for the next-to-leading term in the $1/m$ expansion of the singlet $Q{\bar Q}$ QCD potential in terms of Wilson loops, which holds beyond perturbation theory. The ambiguities in the definition of the QCD potential beyond leading order in $1/m$ are discussed and a specific expression for the $1/m$ potential is given. We explicitly evaluate this expression at one loop and compare the outcome with the existing perturbative results. On general grounds we show that for quenched QED and fully Abelian-like models this expression exactly vanishes.Comment: 19 pages, LaTeX, 1 figure. Journal version. Discussion refined, misprints corrected, few references added; results unchange

A Membrane Defect in the Pathogenesis of the Smith-Lemli-Opitz Syndrome

The Smith-Lemli-Opitz syndrome (SLOS) is an often lethal birth defect resulting from mutations in the gene responsible for the synthesis of the enzyme 3beta-hydroxy-steroid-Delta7-reductase, which catalyzes the reduction of the double bond at carbon 7 on 7-dehydrocholesterol (7-DHC) to form unesterified cholesterol. We hypothesize that the deficiency in cholesterol biosynthesis and subsequent accumulation of 7-DHC in the cell membrane leads to defective composition, organization, dynamics, and function of the cell membrane. Using skin fibroblasts obtained from SLOS patients, we demonstrate that the SLOS membrane has increased 7-DHC and reduced cholesterol content and abnormal membrane fluidity. X-ray diffraction analyses of synthetic membranes prepared to mimic SLOS membranes revealed atypical membrane organization. In addition, calcium permeability is markedly augmented, whereas membrane-bound Na+/K+ATPase activity, folate uptake, inositol-1,4,5-trisphosphate signaling, and cell proliferation rates are markedly suppressed. These data indicate that the disturbance in membrane sterol content in SLOS, likely at the level of membrane caveolae, directly contributes to the widespread tissue abnormalities in this disease

Renormalization group analysis of the QCD quark potential to order v^2

A one-loop renormalization group analysis of the order v^2 relativistic corrections to the static QCD potential is presented. The velocity renormalization group is used to simultaneously sum ln(m/mv) and ln(m/mv^2) terms. The results are compared to previous calculations in the literature.Comment: 13 pages. important change: running of soft Lagrangian include

Spectral and spatial observations of microwave spikes and zebra structure in the short radio burst of May 29, 2003

The unusual radio burst of May 29, 2003 connected with the M1.5 flare in AR 10368 has been analyzed. It was observed by the Solar Broadband Radio Spectrometer (SBRS/Huairou station, Beijing) in the 5.2-7.6 GHz range. It proved to be only the third case of a neat zebra structure appearing among all observations at such high frequencies. Despite the short duration of the burst (25 s), it provided a wealth of data for studying the superfine structure with millisecond resolution (5 ms). We localize the site of emission sources in the flare region, estimate plasma parameters in the generation sites, and suggest applicable mechanisms for interpretating spikes and zebra-structure generation. Positions of radio bursts were obtained by the Siberian Solar Radio Telescope (SSRT) (5.7 GHz) and Nobeyama radioheliograph (NoRH) (17 GHz). The sources in intensity gravitated to tops of short loops at 17 GHz, and to long loops at 5.7 GHz. Short pulses at 17 GHz (with a temporal resolution of 100 ms) are registered in the R-polarized source over the N-magnetic polarity (extraordinary mode). Dynamic spectra show that all the emission comprised millisecond pulses (spikes) of 5-10 ms duration in the instantaneous band of 70 to 100 MHz, forming the superfine structure of different bursts, essentially in the form of fast or slow-drift fibers and various zebra-structure stripes. Five scales of zebra structures have been singled out. As the main mechanism for generating spikes (as the initial emission) we suggest the coalescence of plasma waves with whistlers in the pulse regime of interaction between whistlers and ion-sound waves. In this case one can explain the appearance of fibers and sporadic zebra-structure stripes exhibiting the frequency splitting.Comment: 11 pages, 5 figures, in press; A&A 201

Running of the heavy quark production current and 1/k potential in QCD

The 1/k contribution to the heavy quark potential is first generated at one loop order in QCD. We compute the two loop anomalous dimension for this potential, and find that the renormalization group running is significant. The next-to-leading-log coefficient for the heavy quark production current near threshold is determined. The velocity renormalization group result includes the alpha_s^3 ln^2(alpha_s) ``non-renormalization group logarithms'' of Kniehl and Penin.Comment: 30 pages, journal versio

The QCD heavy-quark potential to order v^2: one loop matching conditions

The one-loop QCD heavy quark potential is computed to order v^2 in the color singlet and octet channels. Several errors in the previous literature are corrected. To be consistent with the velocity power counting, the full dependence on |p' + p|/|p' - p| is kept. The matching conditions for the NRQCD one-loop potential are computed by comparing the QCD calculation with that in the effective theory. The graphs in the effective theory are also compared to terms from the hard, soft, potential, and ultrasoft regimes in the threshold expansion. The issue of off-shell versus on-shell matching and gauge dependence is discussed in detail for the 1/(m k) term in the potential. Matching on-shell gives a 1/(m k) potential that is gauge independent and does not vanish for QED.Comment: 28 pages, References added and minor changes to section III, results unchange